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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF7
All Species:
19.7
Human Site:
S431
Identified Species:
43.33
UniProt:
Q8N684
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N684
NP_001129512.1
471
52050
S431
R
E
R
S
P
S
R
S
R
E
S
S
R
R
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082435
519
57231
S479
R
E
R
S
P
S
R
S
R
E
S
S
R
R
H
Dog
Lupus familis
XP_533274
514
56498
S474
R
E
R
S
P
S
R
S
R
E
S
S
R
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTV2
471
51993
S431
R
E
R
S
P
S
R
S
R
E
S
S
R
R
H
Rat
Rattus norvegicus
Q5XI29
462
51054
S422
R
E
R
S
P
S
R
S
R
E
S
S
R
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL34
551
59341
R508
R
S
R
E
K
S
R
R
H
K
S
R
S
R
D
Frog
Xenopus laevis
Q6DDW4
548
59387
R504
S
R
S
R
E
K
S
R
R
H
K
S
R
S
R
Zebra Danio
Brachydanio rerio
Q6NWC6
545
58757
R501
S
R
S
R
E
K
S
R
R
H
K
S
R
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSH4
652
71076
T542
R
Q
R
R
E
R
S
T
S
R
Y
R
E
R
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_501551
489
53643
E462
R
D
R
S
R
S
R
E
R
D
R
K
R
R
R
Sea Urchin
Strong. purpuratus
XP_782654
898
96357
E841
G
S
R
E
R
D
P
E
N
R
H
R
S
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.2
89.4
N.A.
98.7
96.5
N.A.
N.A.
44.2
43.9
44.5
N.A.
34.8
N.A.
31.2
21.8
Protein Similarity:
100
N.A.
84.3
89.8
N.A.
99.3
97.2
N.A.
N.A.
56.8
56.2
58.1
N.A.
46.1
N.A.
47.4
34.5
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
40
20
20
N.A.
20
N.A.
53.3
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
46.6
20
20
N.A.
33.3
N.A.
66.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
10
0
0
0
10
0
0
0
0
10
% D
% Glu:
0
46
0
19
28
0
0
19
0
46
0
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
19
10
0
0
0
46
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
19
0
0
0
10
19
10
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
46
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
73
19
82
28
19
10
64
28
73
19
10
28
73
82
28
% R
% Ser:
19
19
19
55
0
64
28
46
10
0
55
64
19
19
10
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _